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Dr. Girish Bathla at the University of Iowa is leading a new study, high resolution and vessel wall imaging in neurosarcoidosis [NS].

The purpose of this research study is to evaluate for presence and severity of vessel wall inflammation in patients with neurosarcoidosis. Unlike routine MRI imaging, the high resolution imaging used in this study is much more sensitive to detect changes like vessel wall inflammation which has been associated with more aggressive disease course and poor outcomes, as well as a higher incidence of strokes and small brain bleeds.

If you agree to take part in this study, your involvement will last for the duration of the MRI scan (at most 60 minutes). This will include part of your routine clinical scan with an extra 20 minutes for obtaining the additional high-resolution images. In case the scan is for research purposes only, the duration of the study will be approximately 30 minutes. You will not need to have more than one MRI scan and there will not be any other follow-up visits needed from the point of view of this study.

The inclusion criteria are:

  • Neurosarcoidosis diagnosis within the last 2 years (either ‘definite’ or ‘probable’ per Zajicek criteria).
  • Age 18-85
  • Able to consent
  • Reliable follow-up

The exclusion criteria are:

  • Any cause of CNS vasculitis other than neurosarcoidosis.
  • Any co-existing intracranial pathology which may confound evaluation of NS, such as infection or metastatic disease.
  • Pregnant/lactating.
  • Poor renal function
  • Allergic to MRI contrast.
  • Unable to undergo MRI due to metallic/non-compatible implants (e.g. Pacemaker, Coronary Stent, Defibrillator, Neurostimulator)

In order to participate, patients need to sign a consent form. They will also get a $50 gift card (Hy-Vee) for participating in the research component. The scan duration is about 40-50 minutes. If you are not a patient a the University of Iowa, you should be prepared to provide a copy of your medical record to study coordinators before your visit.

If you have read the inclusion and exclusion criteria, are willing to travel to Iowa City to participate, and think you qualify, please contact or complete the form if you wish for FSR to pass on your information to the study coordinator: 

Girish Bathla (preferred)
Elina Shrestha

  • FSR is interested in knowing more about your ethnicity background as we continue to strive for diversity and inclusion. Please indicate which best describes you (select one):

The Foundation for Sarcoidosis Research [FSR] is proud to fund this research study.  

Choosing to participate in a study is an important decision we encourage you to discuss with your physicians, family members, and friends. Every study comes with potential risks and benefits you should discuss thoroughly with your physicians and study coordinators.


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